US · USD

VRTX

Vertex Pharmaceuticals Inc

US$522.81-0.74% (-US$3.92)
Day's range
US$522.74 – US$529.72
Day's volume
US$587.3m
52-week range
US$402.90 – US$557.96

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VRTX in numbers

Market cap
US$132.5bn
P/E
30.08
P/B
6.54
Dividend yield (12m)
0.00%

VRTX trades at 30.08 times its earnings of the last 12 months.

VRTX price history

01/10/202530/09/2026
Compare with

VRTX risk and return

Monthly closes adjusted for splits and distributions.

Metric12 months36 months60 months
Return+33.38%+50.22%+187.99%
Volatility (annualised)24.64%26.69%25.57%
Largest drawdown-13.98%-23.25%-23.25%
Positive months8/1223/3639/60

How much did investing in VRTX return?

US$1,000.00 invested on 01/09/2021 would be worth US$2,879.87 today.

Value today in VRTX
US$2,879.87
Return over the period
+187.99%
Return per year
+23.56%
In the S&P 500
US$1,788.52

With dividends reinvested, before taxes and costs, at month-end closes. Past returns do not guarantee future ones.

VRTX fundamentals

Valuation

  • P/E
    30.08
  • P/B
    6.54
  • EV/EBITDA
    26.51
  • EV/EBIT
    27.74
  • EV/Revenue
    10.53
  • P/EBIT
    27.74
  • P/S
    10.53
  • P/OCF
    30.87
  • P/FCF
    34.91
  • Earnings yield
    3.61%
  • PEG ratio
    —
  • Earnings per share
    US$17.38
  • Book value per share
    US$79.89

Debt

  • Net debt
    —
  • Net debt/EBITDA
    —
  • Net debt/Equity
    —
  • Debt/Equity
    —
  • Current ratio
    3.19
  • Quick ratio
    2.74
  • Cash ratio
    1.99

Efficiency

  • Gross margin
    86.00%
  • EBITDA margin
    39.72%
  • Operating margin
    37.95%
  • Net margin
    35.00%
  • Asset turnover
    0.46

Profitability

  • ROE
    21.76%
  • ROA
    16.06%
  • ROIC
    19.70%
  • Payout
    0.00%

Growth

  • Revenue CAGR (5 years)
    13.50%
  • Earnings CAGR (5 years)
    17.21%
  • Revenue growth (year)
    —
  • Earnings growth (year)
    —
  • Revenue growth (quarter)
    —
  • Earnings growth (quarter)
    —

What is VRTX's fair price?

Two classic value formulas, with today's numbers. The current price is US$522.81.

Graham's fair price
US$176.75
66.19% below the price

√(22.50 × US$17.38 × US$79.89)

Benjamin Graham paid no more than a P/E of 15 and a P/B of 1.5. Their product, 22.5, times earnings (EPS) and book value per share gives the fair price.

Bazin's ceiling price
—
Does not apply to VRTX: it paid no distributions in the last five years.

Décio Bazin only bought shares yielding at least 6% a year in distributions. The ceiling price is the average dividend per share of recent years divided by 6%.

Graham ignores growth and debt; Bazin assumes past distributions will repeat. They are reference points for comparison, not a buy recommendation.

VRTX indicators by year

Multiples at each year's closing price; margins and returns from that year's accounts.

Indicator20252024202320222021202020192018
P/E29.13-193.0729.0422.3523.8722.6648.2420.20
P/B6.176.305.985.345.547.079.339.55
EV/EBITDA26.28—26.1916.6619.2320.7243.5259.87
Earnings per shareUS$15.56-US$2.09US$14.01US$12.92US$9.20US$10.43US$4.54US$8.20
Book value per shareUS$73.48US$63.90US$68.06US$54.12US$39.67US$33.42US$23.47US$17.35
ROE21.18%-3.26%20.59%23.88%23.19%31.22%19.34%47.28%
ROIC19.04%0.00%18.01%24.30%23.63%28.61%16.60%14.32%
Gross margin86.24%86.11%87.21%87.90%88.06%88.14%86.84%86.56%
EBITDA margin36.52%-0.23%40.66%49.89%38.39%47.79%31.33%23.22%
Net margin32.94%-4.86%36.68%37.20%30.92%43.70%28.27%68.80%

VRTX financial statements

Line202520242023202220212020
Net revenueUS$12bnUS$11bnUS$9.9bnUS$8.9bnUS$7.6bnUS$6.2bn
Cost of sales-US$1.7bn-US$1.5bn-US$1.3bn-US$1.1bn-US$904.2m-US$736.3m
Gross profitUS$10.4bnUS$9.5bnUS$8.6bnUS$7.9bnUS$6.7bnUS$5.5bn
EBITDAUS$4.4bn-US$25.7mUS$4bnUS$4.5bnUS$2.9bnUS$3bn
EBITUS$4.2bn-US$232.9mUS$3.8bnUS$4.3bnUS$2.8bnUS$2.9bn
Net finance result——————
Profit before taxUS$4.6bnUS$248.5mUS$4.4bnUS$4.2bnUS$2.7bnUS$3.1bn
Income tax-US$690m-US$784.1m-US$760.2m-US$910.4m-US$388.3m-US$405.2m
Net incomeUS$4bn-US$535.6mUS$3.6bnUS$3.3bnUS$2.3bnUS$2.7bn

Figures the company filed with the CVM. Debt excludes leases; each quarter is that quarter alone.

Does VRTX pay dividends?

VRTX has no distributions on record.

About Vertex Pharmaceuticals

Sector
Manufacturing

Questions about VRTX

How much is VRTX today?

VRTX is at US$522.81 (-0.74% on the day), last traded on 30/09/2026.

What are the P/E and P/B of VRTX?

VRTX trades at a P/E of 30.08 and a P/B of 6.54.

How much did VRTX return in 12 months?

VRTX returned 33.38% in 12 months, with annualised volatility of 24.64% and a largest drawdown of -13.98%.