US · USD

AXSM

Axsome Therapeutics Inc

$174.34-1.55% (-$2.74)
Day's range
$169.30 – $176.52
Day's volume
$238.5M
52-week range
$118.64 – $255.17

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AXSM in numbers

Market cap
$9.1B
P/E
-47.65
P/B
109.62
Dividend yield (12m)
0.00%

AXSM price history

10/07/202510/06/2026
Compare with

AXSM risk and return

Monthly closes adjusted for splits and distributions.

Metric12 months36 months60 months
Return+15.08%+158.47%+404.75%
Volatility (annualized)40.36%37.63%63.93%
Largest drawdown-28.77%-28.77%-39.60%
Positive months6/1219/3633/60

How much did investing in AXSM return?

$1,000.00 invested on 11/01/2021 would be worth $5,047.48 today.

Value today in AXSM
$5,047.48
Return over the period
+404.75%
Return per year
+38.89%
In the S&P 500
$1,712.05

With dividends reinvested, before taxes and costs, at month-end closes. Past returns do not guarantee future ones.

AXSM fundamentals

Valuation

  • P/E-47.65
  • P/B109.62
  • EV/EBITDA—
  • EV/EBIT-48.37
  • EV/Revenue11.59
  • P/EBIT-49.08
  • P/S11.76
  • P/OCF-128.15
  • P/FCF-126.91
  • Earnings yield-2.07%
  • PEG ratio—
  • Earnings per share-$3.66
  • Book value per share$1.59

Debt

  • Net debt-$131.9M
  • Net debt/EBITDA—
  • Net debt/Equity-1.58
  • Debt/Equity2.26
  • Current ratio1.43
  • Quick ratio1.34
  • Cash ratio0.69

Efficiency

  • Gross margin—
  • EBITDA margin—
  • Operating margin-23.96%
  • Net margin-24.68%
  • Asset turnover1.02

Profitability

  • ROE-230.05%
  • ROA-25.17%
  • ROIC—
  • Payout—

AXSM's indicators by year

Multiples at each year's closing price; margins and returns from that year's statements.

Indicator20252024202320222021202020192018
P/E-51.00-14.37-15.76-17.94-11.15-29.62-56.07-3.03
P/B105.8172.3719.7430.6493.0026.7821.44100.06
Earnings per share-$3.58-$5.89-$5.05-$4.30-$3.39-$2.75-$1.84-$0.93
Book value per share$1.73$1.17$4.03$2.52$0.41$3.04$4.82$0.03
ROE-207.46%-503.76%-125.27%-170.81%-834.26%-90.43%-38.24%-3,301.50%
ROIC———-6,047.73%———-276.21%
Gross margin———89.61%————
Net margin-28.69%-74.47%-88.41%-373.99%————

AXSM's financial statements

Line202520242023202220212020
Net revenue$638.5M$385.7M$270.6M$50M——
Cost of revenue———-$5.2M——
Gross profit———$44.8M——
EBITDA——————
EBIT-$166.8M-$280.6M-$231.8M-$179.8M-$124.7M-$99.1M
Financial result——————
Income before tax-$183.7M-$287.1M-$238.3M-$187.1M-$130.4M—
Income tax$530K-$85K-$960K-$0-$0-$0
Net income-$183.2M-$287.2M-$239.2M-$187.1M-$130.4M-$102.9M

Figures the company filed with the CVM. Debt excludes leases; each quarter is that quarter alone.

Does AXSM pay dividends?

AXSM has no distributions on record.

About Axsome Therapeutics

Sector
Manufacturing

Questions about AXSM

How much is AXSM today?

AXSM is at $174.34 (-1.55% on the day), last traded on 10/06/2026.

What are the P/E and P/B of AXSM?

AXSM trades at a P/E of -47.65 and a P/B of 109.62.

How much did AXSM return in 12 months?

AXSM returned 15.08% in 12 months, with annualized volatility of 40.36% and a largest drawdown of -28.77%.