US · USD

PTGX

Protagonist Therapeutics Inc

$138.69-1.38% (-$1.94)
Day's range
$136.09 – $141.00
Day's volume
$87.2M
52-week range
$65.30 – $158.62

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PTGX in numbers

Market cap
$9B
P/E
108.24
P/B
10.66
Dividend yield (12m)
0.00%

PTGX trades at 108.24 times its earnings of the last 12 months.

PTGX price history

10/07/202510/06/2026
Compare with

PTGX risk and return

Monthly closes adjusted for splits and distributions.

Metric12 months36 months60 months
Return+54.10%+661.61%+312.52%
Volatility (annualized)33.23%38.18%57.74%
Largest drawdown-9.11%-18.00%-76.87%
Positive months6/1222/3632/60

How much did investing in PTGX return?

$1,000.00 invested on 11/01/2021 would be worth $4,125.22 today.

Value today in PTGX
$4,125.22
Return over the period
+312.52%
Return per year
+33.32%
In the S&P 500
$1,712.05

With dividends reinvested, before taxes and costs, at month-end closes. Past returns do not guarantee future ones.

PTGX fundamentals

Valuation

  • P/E108.24
  • P/B10.66
  • EV/EBITDA149.87
  • EV/EBIT153.82
  • EV/Revenue31.82
  • P/EBIT153.82
  • P/S31.82
  • P/OCF68.40
  • P/FCF68.73
  • Earnings yield0.65%
  • PEG ratio—
  • Earnings per share$1.28
  • Book value per share$13.01

Debt

  • Net debt—
  • Net debt/EBITDA—
  • Net debt/Equity—
  • Debt/Equity—
  • Current ratio21.71
  • Quick ratio—
  • Cash ratio21.05

Efficiency

  • Gross margin—
  • EBITDA margin21.24%
  • Operating margin20.69%
  • Net margin29.40%
  • Asset turnover0.32

Profitability

  • ROE9.85%
  • ROA9.36%
  • ROIC6.82%
  • Payout0.00%

Growth

  • Revenue CAGR (5 years)59.62%
  • Earnings CAGR (5 years)—
  • Revenue growth (year)—
  • Earnings growth (year)—
  • Revenue growth (quarter)—
  • Earnings growth (quarter)—

What is PTGX's fair price?

Two classic value formulas, with today's numbers. The current price is $138.69.

Graham's fair price
$19.36
86.04% below the price

√(22.50 × $1.28 × $13.01)

Benjamin Graham paid no more than a P/E of 15 and a P/B of 1.5. Their product, 22.5, times earnings (EPS) and book value per share gives the fair price.

Bazin's ceiling price
—
Does not apply to PTGX: it paid no distributions in the last five years.

Décio Bazin only bought stocks yielding at least 6% a year in distributions. The ceiling price is the average dividend per share of recent years over 6%.

Graham ignores growth and debt; Bazin assumes past distributions repeat. They are references to compare, not a buy recommendation.

PTGX's indicators by year

Multiples at each year's closing price; margins and returns from that year's statements.

Indicator20252024202320222021202020192018
P/E-42.828.61-16.92-4.39-13.19-13.35-2.49-4.04
P/B9.073.513.972.595.523.162.411.40
EV/EBITDA—9.34——————
Earnings per share-$2.04$4.48-$1.35-$2.48-$2.59-$1.51-$2.83-$1.67
Book value per share$9.63$11.00$5.78$4.20$6.20$6.38$2.93$4.82
ROE-21.17%40.75%-23.45%-59.09%-41.85%-23.66%-96.53%-34.59%
ROIC-25.72%36.88%-27.82%-60.93%-41.95%-23.07%—-36.81%
EBITDA margin-340.85%58.39%-154.46%-490.35%-457.04%-222.05%-34,540.69%-134.98%
Net margin-282.83%63.34%-131.59%-479.26%-458.93%-231.07%-33,414.29%-125.87%

PTGX's financial statements

Line202520242023202220212020
Net revenue$46M$434.4M$60M$26.6M$27.4M$28.6M
Cost of revenue——————
Gross profit——————
EBITDA-$156.8M$253.7M-$92.7M-$130.3M-$125M-$63.6M
EBIT-$158.1M$252.8M-$93.7M-$131.4M-$125.8M-$64.5M
Financial result——————
Income before tax-$129.3M$279.4M-$79M-$127.4M-$125.6M-$64.8M
Income tax-$838K-$4.2M-$0-$0-$0-$1.3M
Net income-$130.1M$275.2M-$79M-$127.4M-$125.6M-$66.2M

Figures the company filed with the CVM. Debt excludes leases; each quarter is that quarter alone.

Does PTGX pay dividends?

PTGX has no distributions on record.

About Protagonist Therapeutics

Sector
Manufacturing

Questions about PTGX

How much is PTGX today?

PTGX is at $138.69 (-1.38% on the day), last traded on 10/06/2026.

What are the P/E and P/B of PTGX?

PTGX trades at a P/E of 108.24 and a P/B of 10.66.

How much did PTGX return in 12 months?

PTGX returned 54.10% in 12 months, with annualized volatility of 33.23% and a largest drawdown of -9.11%.